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Mixing AstraZeneca and Pfizer shots triggers more fatigue, headaches — findings

May 13): Mixing doses of two leading Covid-19 vaccines increased patients’ side effects such as fatigue and headaches in early findings from a study that has yet to show how well such a cocktail defends against the virus.

People who got a first dose of AstraZeneca Plc’s shot followed by Pfizer Inc.’s vaccine four weeks later reported more short-lived side effects, most of them mild, researchers from the University of Oxford reported in The Lancet medical journal. That was also true when the order of the shots was switched.

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